HGH and Metabolism
The relationship between Human Growth Hormone and Metabolism has been well researched into established. The protein, lipid and carbohydrate metabolism is either directly affected or through a mediator like IGF-1 (insulin like growth factor -1). In some cases, both direct and indirect effects can be observed. The term metabolism, to a layman would mean the process by which the food we eat is broken down and converted into energy to be utilized by the body. It is essential to have a healthy metabolic function, as it helps in digesting the food we eat and prevents us from becoming fat and obese. Aging has its effect on the rate of metabolism. With age, the ability of the body to burn food reduces and this increases the risk of obesity and even degeneration of organs including the digestive system. The reduction of metabolism has been linked with the reduction in the levels of human growth hormone produced in the body. Past the age of 30, the production of HGH in our bodies reduces. We shall look into a few of the metabolisms and how the HGH influences each of them.
The HGH stimulates the metabolism of proteins both directly and indirectly. Growth hormone stimulates protein anabolism in many tissues which increases amino acid uptake and decreases oxidation of proteins. The indirect action of HGH occurs through the mediation of IGF-1. IGF-1 has been clinically proven to increase the demand of proteins in the body due to its action of strengthening the muscles. This more demand results in the faster metabolism of proteins.
The fat metabolism is enhanced by the stimulation of triglyceride breakdown and oxidation in adipocytes by the action of HGH.
Growth hormone is one of the important hormones that regulate the level of glucose in the blood to a normal range. The activity of HGH is suppresses the abilities of insulin to stimulate uptake of glucose in peripheral tissues and enhance glucose synthesis in the liver. The activity is often referred to as being anti-insulin. However administration of growth hormone stimulates insulin secretion, leading to hyperinsulinemia. For this reason, HGH is rarely administered to diabetes patients as it may cause complications of various kinds.
HGH, in a recent study, was found to reduce LDL cholesterol and this reduction correlated with increased mRNA expression of the LDL receptor in the liver. The potential benefit of this interaction is still not completely understood as it required to be investigated in longer term clinical trials. It must however be noted that such dramatic changes in lipid levels are not associated with GH administration on a consistent basis.
The link between the HGH and metabolism means that it is essential for the people past the age of 30 to well identify its importance and take steps to ensure that the healthy levels of metabolism is maintained and its ill effects avoided. The metabolic rate is determined by three factors. The first is the MBR, or the basal metabolic rate, which is the measure of the rate at which the body utilizes the energy for essential processes like breathing. The second is the rate at which the body burns calories while doing any physical activity like running, jumping etc. This is the rate that can be enhanced by increasing the physical activity and the amount of exercise that an individual does. The third rate is the thermogenic effect, the rate at which one burns energy during digestive processes.
With age, the metabolism rates may get weakened. One way of resurrecting it is through administering HGH to the body through injection or other forms. This might be essential to many, especially to the elderly. However, other ways of maintaining a healthy metabolic rate is through eating right, regular exercise and staying away from vices.